Oral appliances (OA) have emerged as the leading alternative to positive airway pressure (PAP) forObstructive Sleep Apnoea (OSA) treatment. There is a strong evidence base demonstrating OA therapy improves OSA in the majority of patients, including some with more severe disease. They are generally well tolerated, and patients often prefer OA over PAP treatment. Despite the superior efficacy of PAP over OA, randomized controlled trials comparing the two indicate similar improvement in health outcomes such, as sleepiness, quality of life, driving performance, blood pressure, and other cardiovascular measures. The evidence base strongly supports the use of OA therapy in the management of OSA.
1. To understand the evidence for oral appliance therapy in the management of OSA.
2. Compare the efficacy and effectiveness of oral appliance therapy and CPAP.
3. Understand the concept of personalised management of OSA based on phenotypic characteristics.